Factors associated with nutritional status in peritoneal dialysis patients

  • I. Dudar SI «Institute of Nephrology NAMS of Ukraine», Kyiv, Ukraine https://orcid.org/0000-0002-4372-8240
  • A. Shymova Kyiv City Scientific and Practical department of nephrology and dialysis
  • I. Shifris SI «Institute of Nephrology NAMS of Ukraine», Kyiv, Ukraine
  • M. Malasaev Kyiv City Scientific and Practical department of nephrology and dialysis
Keywords: peritoneal dialysis, nutritional status, subjective global assessment, residual renal function, peritonitis


The aim of our study was to examine the relationship between nutritional status (NS) in patients undergoing continuous ambulatory peritoneal dialysis (CAPD) and dialysis-related factors.Methods. 105 patients who were treated by CAPD were included in this observational study. To assess the NS we determined the level of serum albumin, body mass index (BMI) and subjective global assessment (SGA). The study was carried out in two stages. At the first stage of the work PD patients’ nutrition status was examined. For further analysis, the patients were divided into four groups according to the condition of the NS: the first group (n = 54) consisted of patients without disturbance of nutrition, the second (n = 27) with mild nutrition disorders, the third (n = 13) - with an average degree and the fourth (n = 11) with a severe degree of malnutrition. At the second stage of the work specialty of the nutritional status and residual renal function, frequency of PD-peritonitis, transport characteristics of the peritoneum were studied.Results. Nutritional disorders were observed in 54 (51.4 %) patients. A mild malnutrition was diagnosed in 28.7 % of patients, medium and severe in 12,38 % and 10,48% of patients, respectively. Parameters of NS, except BMI, were higher in patients without nutrition disorders (ND) comparing with the patients who had it. RRF was higher in patients without ND; but anuria was observed practically in all patients with severe ND. We receive direct relationship between the level of serum albumin and RRF (r = 0.53; p <0,001), and SGA and RRF (r = 0.52; p <0,001). Number of PD – peritonitis was lower in patients with normal NS and the highest in patients with severe ND. Strong correlation between the level of serum albumin, SGA, and the frequency and duration of peritonitis was established (r = - 0.59; p<0,001 and r = - 0.59; p <0,001 respectively). High transport characteristic of peritoneum was associated with lower degree of serum albumin and SGA (p <0,001). There was no relationship established between SGA, serum albumin, BMI, age, duration of CAPD treatment, gender, and main nosology.Conclusions: Thus, ND were diagnosed in more than 50% of the examined patients. ND were associated with reduce of RRF, frequency and duration of PD-peritonitis, high transport characteristics of the peritoneum. There was no correlation between level of serum albumin, SGA and gender, duration of CAPD, main nosology and age. BMI did not have correlation with any parameters. The received data testify the necessity of constant monitoring of laboratory and functional parameters of the nutrition status.


Download data is not yet available.


Kolesnyk MO, hol. redaktor. Natsionalnyi reiestr khvorykh na khronichnu khvorobu nyrok ta patsiientiv z  hostrym poshkodzhenniam nyrok: 2017 rik / uklad. NI Kozliuk, SS Nikolaienko, OО Razvazhaieva; Derzhavna ustanova «Instytut nefrolohii NAMN Ukrainy». Kyiv; 2018.183 s. [In Ukrainian].

Sakaci T, Ahbap E, Koc Y, Basurk T, Ucar Z, Sinangil A, et al. Clinical outcomes and mortality in elderly peritoneal dialysis patients. Clinics Sao Paulo. 2015; May 70(5): 363–368. doi: 10.6061/clinics/2015(05)10.

Shymova A, Dudar I, Shifris I. Nutrytsiini rozlady u khvorykh na khronichnu khvorobu nyrok 5D stadii yaki likuiutsia postiinym ambulatornym perytonealnym dializom ta yikh zviazok z hidratatsiinym statusom. Ukrainskyi zhurnal nefrolohii ta dializu. 2018. Vydannia 57. – S.24-32. [In Ukrainian]. doi:10.31450/ukrjnd.1(57).2018.01.

Abdu A. The nutritional status of continuous ambulatory peritoneal dialysis    patients at a Johannesburg hospital. S Afr J Clin Nutr. 2011; Sept. 24(3):150-153. doi: 10.1080/16070658.2011.11734367}

Naeeni A, Poostiyan N, Teimouri Z, Mortazavi M, Soqhrati M, Poostiyan E. Assessment of Severity of Malnutrition in Peritoneal Dialysis Patients via Malnutrition. Adv Biomed Res. 2017; July 6: 128. doi: 10.4103/abr.abr_554_13.

Liu X, Dai C. Advances in Understanding and Management of Residual Renal Function in Patients with Chronic Kidney Disease. Kidney Dis (Basel). 2017; Jan 2(4): 187–196. doi: 10.1159/000449029.

Perl J, Bargman J. The importance of residual kidney function for patients on dialysis: a critical review. Am J Kidney Dis. 2009; Dec 53:1068-1081.  doi:10.1053/j.ajkd.2009.02.012.

Li-Tao W. Strong Association Between Volume Status and Nutritional Status in Peritoneal Dialysis Patients. Am J Kidney Dis. 2005; May 45(5):891-902 doi: 10.1053/j.ajkd.2005.01.037

Shifris IM, Dudar IO. Comorbidity and survival of patients with chronic kidney disease of 5D stage. Ukrainian journal of nephrology and dialysis. 2015, 4 (48):30-39. doi: 10.31450/ukrjnd.4(48).2015.06.

Wang A, Sea M, Ip R, Law M. Independent Effects of Residual Renal Function and Dialysis Adequacy on Actual Dietary Protein, Calorie, and Other Nutrient Intake in Patients on Continuous Ambulatory Peritoneal Dialysis. J Am Soc Nephrol. 2001; Nov 12: 2450–2457. Available from: https://jasn.asnjournals.org/content/12/11/2450.long  

Boudville N, Kemp A, Clayton P, Lim W. Recent peritonitis associates with mortality among patients treated with peritoneal dialysis. J Am Soc Nephrol. 2012; August 23:1398–405. doi: 10.1681/ASN.2011121135.

Chung S, Koh E, Shin S, Park C. Malnutrition in patients with chronic kidney disease. Open J. Intern. Med. 2012; March 2: 89–99. doi: 10.4236/ojim.2012.22018.

 Johansson L. Nutrition in Older Adults on Peritoneal Dialysis. Perit Dial Int. 2015; Nov 35(6): 655–658. doi: 10.3747/pdi.2014.00343.

Guan Li, Bian W, Zhang X. Influence of Peritoneal Transport Characteristics on Nutritional Status and Clinical Outcome in Chinese Diabetic Nephropathy Patients on Peritoneal Dialysis. Chin Med J (Engl). 2015; Apr 5: 859–864. doi: 10.4103/0366-6999.154275.

 Liu Y, Huang R, Guo Q, Yang Q, Yi C, Lin J, Yu X. Baseline higher peritoneal transport had been associated with worse nutritional status of incident continuous ambulatory peritoneal dialysis patients in Southern China: a 1-year prospective study. Br J Nutr. 2015; Aug 14;114(3):398-405 doi: 10.1017/S0007114515001804.

Johansson L. Nutrition in Older Adults on Peritoneal Dialysis. Perit Dial Int. 2015; Nov 35(6): 655–658. doi: 10.3747/pdi.2014.00343.

Carrera-Jiménez D, Miranda-Alatriste P. Relationship between Nutritional Status and Gastrointestinal Symptoms in Geriatric Patients with End-Stage Renal Disease on Dialysis Nutrients. 2018; Mar 29;10(4) 10: 425-431 doi: 10.3390/nu10040425.

Passadakis P, Thodis E. Nutrition in diabetic patients undergoing continuous ambulatory peritoneal dialysis. Peritoneal Dialysis International. 2010; April 19: 27-32. doi: 10.1111/j.1525-139X.2010.00707.x

Abstract views: 72
PDF Downloads: 41
How to Cite
Dudar, I., Shymova, A., Shifris, I., & Malasaev, M. (2018). Factors associated with nutritional status in peritoneal dialysis patients. Ukrainian Journal of Nephrology and Dialysis, (4(60), 19-27. https://doi.org/10.31450/ukrjnd.4(60).2018.03