Peritoneal dialysis - associated peritonitis during treatment with continuous ambulatory peritoneal dialysis

  • M. Malasaiev Municipal nonprofit enterprise «Kyiv city center of nephrology and dialysis»
  • I. Dudar SI «Institute of Nephrology of the National Academy of Medical Sciences» https://orcid.org/0000-0002-4372-8240
  • A. Shymova Municipal nonprofit enterprise «Kyiv city center of nephrology and dialysis»
Keywords: кenal substitution therapy, permanent outpatient peritoneal dialysis, complication, recurrent peritonitis.

Abstract

 Infections associated with peritoneal dialysis (infection of the catheter, tunnel infection and peritonitis) are the most common complications of this method. Despite significant progress in the methodological approaches to the prevention, diagnosis and treatment of PD associated infections, peritonitis remains the main risk factor for mortality in PD patients (up to 6%) and plays a significant role in more than 1/6 of the deaths associated with non-infectious complications such as cardiovascular and / or cerebrovascular disease. Besides, PD-associated infections are the most common cause of loss of peritoneal function and the patients’ transition to hemodialysis treatment. About 5% of PD patients are converted to hemodialysis treatment in the first year after postponed peritonitis.

Downloads

Download data is not yet available.

References

1. Kolesnyk MO, hol. redaktor. Natsionalnyi reiestr khvorykh na khronichnu khvorobu nyrok ta patsiientiv z hostrym poshkodzhenniam nyrok: 2017 rik / uklad. NI Kozliuk, SS Nikolaienko, OО Razvazhaieva; Derzhavna ustanova «Instytut nefrolohii NAMN Ukrainy». Kyiv; 2018.183 s. [In Ukrainian].

2. Sakaci T, Ahbap E, Koc Y, Basurk T, Ucar Z, Sinangil A, et al. Clinical outcomes and mortality in elderly peritoneal dialysis patients. Clinics Sao Paulo. 2015; May 70(5): 363–368. doi: 10.6061.

3. Olivier D,Peter M, Nicholas T. The pathophysiology of the peritoneal membrane. JASN. 2010; July 21(7):1077-1085. doi: 10.1681/ASN.2009070694.

4. I, Burkart J. Peritoneal dialysis. AJKD. 2013;22(5):1082-1096. doi: 10.1016/j.ajkd.2013.08.036.

5. François K, Bargman J. Evaluating the benefits of home-based peritoneal dialysis. Int J Nephrol Renovasc Dis. 2014;7:447-455. doi: 10.2147/IJNRD.S50527.

6. Akoh J. Peritoneal dialysis associated infections: an update on diagnosis and management. World J Nephrol. 2012; Aug 1(4):106-122. doi: 10.5527/wjn.v1.i4.106.

7. Peppelenbosch A. Kuijk W, Bouvy N. Peritoneal dialysis catheter placement technique and complications. ND Plus. 2008;1(4):23-28. doi.org/10.1093/ndtplus/sfn120.

8. Hsieh Y. Wang S, Chang C. The negative Impact of early peritonitis on continuous ambulatory peritoneal dialysis patients. Perit Dial Int. 2014; 34(6):627–635. doi: 10.3747/pdi.2013.00024.

9. Nakaz MOZ Ukrainy vid 11.02.2016 № 89. «Profilaktyka, diahnostyka ta likuvannia infektsii, asotsiiovanykh z perytonealnym dializom».

10. Ballinger A, Palmer S, Wiggins K. Treatment for peritoneal dialysis-associated peritonitis. Cochrane Database of Systematic Reviews. 2014;26(4):54-96. doi:10.1002/14651858:CD005284.pub3.

11. Diepen A, Tomlinson G. The association between exit site infection and subsequent peritonitis among peritoneal dialysis patients. Clin J Am Soc Nephrol. 2012;7(8):1266–71. doi: 10.2215/CJN.00980112.

12. Li PK, Szeto CC, Piraino B, et al. ISPD peritonitis recommendations: 2016 Update on prevention and treatment. Perit Dial Int. 2016;36(5):481-508.doi: 10.3747/pdi.2016.00078

13. Boudville N, Kemp A, Clayton P, Lim W. J AmSocNephrol. 2012; August 23:1398–405.doi:10.1681/ASN.2011121135.

14. Crabtree">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803364/">Crabtree J, Siddiqi R. Simultaneous catheter replacement for infectious and mechanical complications without interruption of Peritoneal Dialysis. Perit Dial Int. 2016;36(2):182-7. doi: 10.3747/pdi.2014.00313.

15. Ratajczak A, Lange-Ratajczak M, Bobkiewicz A, Studniarek A. Surgical Management of complications with peritoneal dialysis. Seminarsin dialysis. 2016;30(1):63–68. doi: 10.1111/sdi.12538.

16. Wong">http://www.pdiconnect.com/content/37/4/475.long">Wong S, Lau W, Chan P. Antibiotic lock in Tenckhoff catheter for Biofilm-Associated Peritonitis. Perit Dial Int. 2017;37(4):475-477. doi: 10.3747/pdi.2016.00252.

17. Kiwon K, Han R, Yun K. Pharmacokinetic Profiles of Ceftazidime after Intravenous Administration in Patients Undergoing Automated Peritoneal Dialysis. Antimicrob Agents Chemother. 2011;55(6):2523–2527. doi: 10.1128/AAC.01543-10.

18. Wong">http://www.pdiconnect.com/content/39/2/187.long">Wong S, Lau W, Chan P, Wan C, Cheng Y. Extended Experience in the use of antibiotic Lock for eradication of biofilm bacteria on Tenckhoff catheter. Perit Dial Int. 2019;39(2):187-190. doi: 10.3747/pdi.2018.00098.

19. Mushahar L, Mei L, Yusuf W, Sivathasan S, Kamaruddin N. Exit-Site dressing and infection in peritoneal dialysis: a randomized controlled pilot trial. PeritDial Int J. 2016; 36(2):135–139. doi: 10.3747/pdi.2014.001954.

20.Taheri S, Ahmadnia M, Mortazavi M, Karimi S, Reihani H. Comparing the effect of dressing versus no dressing on exit site infection and peritonitis in chronic ambulatory peritoneal dialysis patients. AdvBiomedRes. 2017;6(5). doi: 10.4103/2277-9175.199263.

21. Szeto C, Li P, Johnson D, Bernardini J, Dong J, Figueiredo A. ISPD catheter-related infection recommendations: 2017 update. Perit Dial Int. 2018; 37(2):141–154. doi: 10.3747/pdi.2016.00120.

22. Viron C, Lobbedez T, Lanot A, Bonamy C, Ficheux M. Simultaneous removal and reinsertion of the PD catheter in relapsing peritonitis. Perit Dial Int. 2019;9:143-52. doi: 10.3747/pdi.2018.00230.

23. Buemi M, Aloisi C, Romeo A, Sturiale A, Barilla' A, Cosentini V. Diverticular disease of the colon in peritoneal dialysis. G Ital Nefrol. 2002;19(5):540-4. doi: 10.3748/wjg.v9.i10.2140.

24. Mihalache O, Buga S.The time for surgery of peritonitis associated with peritoneal dialysis. J Med Life. 2016;9(3):284–7.

25. Salzer W. Peritoneal dialysis-related peritonitis: challenges and solutions. Int J Nephrol Renovasc Dis. 2018;11:173-186. doi: 10.2147/IJNRD.S123618.

26. Boudville N, Kemp A, Clayton P, Lim W. Recent peritonitis associates with mortality among patients treated with peritoneal dialysis. J Am Soc Nephrol. 2012;23:1398–405. doi:10.1681/ASN.2011121135.

27. Kam-Tao Li P, Szeto C, Piraino B, Arteaga J. ISPD peritonitis recommendations: 2016 update on prevention and treatment. Perit Dial Int. 2016;36:481-508. doi: 10.3747/pdi.2016.00078.

28. Kakuta T, Tanaka R, Satoh Y, Izuhara Y. Pyridoxamine improves functional, structural, and biochemical alterations of peritoneal membranes in uremic peritoneal dialysis rats. Kidney Int. 2005;68(3):1326-36. doi: 10.1111/j.1523-1755.2005.00531.x.

29. Wu J, Xing C, Zhang L, Mao H, Chen X, Liang M. Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis. J Cell Mol Med.2017;3(17):43-52. doi:10.1111/jcmm.13393.

30. Simon F, Tapiа P, Armisen R, Echeverria C, Gatica S. Human peritoneal mesothelial cell death induced by High-Glucose hypertonic solution involves Ca2+ and Na+ ions and oxidative stress with the participation of PKC/NOX2 and PI3K/Akt pathways. Frontiersin physiology, 2017;8:92-105. doi: 10.3389/fphys.2017.00379. 

31. Balteau M, Tajeddine N, Meester C, Ginion A. NADPH oxidase activation by hyper glycaemia in cardiomyocytes is independent of glucose metabolism but requires SGLT1. Cardiovasc. Res. 2011;92:237–246. doi: 10.1093/cvr/cvr230.

32. García L, Lindholm B, Davies S. An update on peritoneal dialysis solutions. Nat. Rev. Nephrol. 2012;8: 224–233. doi:10.1038/nrneph.2012.13.

33. Liakopoulos V, Roumeliotis S, Gorny X, Eleftheriadis T, Mertens P. Oxidative stress in patients undergoing peritoneal dialysis. A current review of the literature. Oxidative medicine and cellular longevity volume. 2017;12: 98-105. doi: org/10.1155/2017/3494867.

34. Guest S. Hypoalbuminemia in peritoneal dialysis patients. Adv Perit Dial. 2013;29:55-60.

35. Jiang J, Wang L, Fei Y. Serum albumin at start of peritoneal dialysis predicts. Long term outcomes in Anhui Han patients on continuous ambulatory peritoneal dialysis.A retrospective cohort study.Kidney Dis. 2018; 4:1-7. doi: 10.1159/000492426.


Abstract views: 622
PDF Downloads: 18030
Published
2019-08-04
How to Cite
Malasaiev, M., Dudar, I., & Shymova, A. (2019). Peritoneal dialysis - associated peritonitis during treatment with continuous ambulatory peritoneal dialysis . Ukrainian Journal of Nephrology and Dialysis, (3(63), 47-52. https://doi.org/10.31450/ukrjnd.3(63).2019.07