STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF THE MYOCARDIUM IN CHILDREN WITH TERMINAL CHRONIC RENAL FAILURE ON DIALYSIS TREATMENT
Abstract
Methods.Morphological and functional state of the myocardium was evaluated in 28 children with terminal chronic renal failure on dialysis treatment.
Results. Normal geometry of the left ventricle was found only in 14.3% of children surveyed. Concentric hypertrophy of the left ventricle (LV) was revealed in 71.4% of patients, excentric hypertrophy - in 10.7 . Signs of cardiac dysfunction were found in 85.7% of children, in 41.7% of them being accompanied with left ventricular cavity dilation. Signs of systolic and diastolic left ventricular dysfunction was found in 58.3% of patients with LV remodeling. Significant dilatation of the LV was strongly associated with the development of left ventricular systolic dysfunction (54.5%) and left ventricular diastolic dysfunction (18.2%). That fact makes it a significant marker of myocardial dysfunction in children with uremic cardiomyopathy.
Conclusions. Concentric left ventricular remodeling pattern revieled to be more favorable and less often accompanied with the development of cardiac dysfunction, unless it is combined with significant dilation of the left ventricle.
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