Global research trends and collaboration networks in arteriovenous fistula bleeding for haemodialysis: A bibliometric analysis (2000–2024)
Abstract
Arteriovenous (AV) fistula is the gold standard for long-term haemodialysis, yet bleeding complications remain frequent, causing anemia, treatment interruption, and hospitalizations. Despite its clinical importance, research on AV fistula bleeding is fragmented across disciplines. This study provides the first global bibliometric analysis exclusively focused on AV fistula bleeding, offering a consolidated view of research trends and gaps. The present study aimed to map global research output, thematic clusters, and emerging trends in AV fistula bleeding over the past two decades.
Methods. Publications from 2000–2025 were retrieved from Scopus and PubMed using predefined keywords via Publish or Perish. After duplicate removal and title/abstract screening, 127 English-language articles met the eligibility criteria. Data were analyzed with VOSviewer (v1.6.19) to create density, network, and overlay visualizations with a minimum threshold of five term occurrences.
Results. From an initial 3,085 records, annual output increased steadily after 2010. The United States, the United Kingdom, and China were the most productive countries, and the Journal of Vascular Access was the leading source. Thematic mapping identified four clusters: (1) clinical complications (hematoma, vascular events), (2) diagnostic and interventional strategies (angiography, embolization), (3) anatomical considerations (vein selection, puncture site), and (4) outcome-based evaluations (patency, safety, quality). Density maps showed persistent focus on hematoma and vascular complications, while overlay maps indicated a post-2020 shift toward patient-centered outcomes and methodological rigor.
Conclusions. Research on AV fistula bleeding has progressed from technical and anatomical themes to patient-safety and quality-of-care priorities. These findings underpin the need for standardized bleeding-management protocols and multidisciplinary collaboration to improve prevention and clinical outcomes.
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