HELLP syndrome against the background of glomerulonephritis: Clinical casereport

  • L. Lebid State Institution «Institute of Nephrology of the National Academy of Medical Sciences»
  • L. Snisar State Institution «Institute of Nephrology of the National Academy of Medical Sciences»
  • L. Liksunova State Institution «Institute of Nephrology of the National Academy of Medical Sciences»
Keywords: HELLP syndrome, chronic kidney disease, glomerulonephritis.

Abstract

 HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets) is a severe and rapidly progressing condition that requires distinct diagnostic considerations. The clinical presentation varied within all of the classes, and the only objective means of diagnosis and evaluation of progression of the condition are laboratory tests. HELLP syndrome may result in severe morbidity and mortality to both the mother and fetus.

In this case, we reported that a patient with chronic glomerulonephritis was diagnosed with HELLP syndrome.The case was collected in Institute of Nephrology of the National Academy of Medical Sciences, Kyiv, Ukraine.

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References

1.Pritchard JA, Weisman R, Jr, Ratnoff OD, Vosburgh GJ. Intravascular hemolysis, thrombocytopenia and other hematological disorders associated with severe pregnancy toxicosis. N Engl J Med. 1954; 250: 89–98. doi: 10.2214/AJR.04.0817

2.Weinstein's syndrome L. Hemolysis, elevation of liver enzymes and low platelet content: a severe consequence of hypertension in pregnancy. 1982. Am J Obstet Gynecol. 2005; 193: 859. doi: 10.1016 / j.ajog.2005.02.113.

3.Audibert F, Friedman SA, Frangieh AY, Sibai BM. Clinical utility of strict diagnostic criteria for AD syndrome (hemolysis, elevated liver enzymes and low platelet count). Am J Obstet Gynecol. 1996; 175: 460–464. doi: 10.1016/S0002-9378 (96) 70162-X.

4.Celik C, Gezginc K, Altintepe L, Tonbul HZ, Yaman ST, Akyurek C, Turk S. Pregnancy outcomes with AD. Ren Fail. 2003; 25: 613–618. doi: 10.1081 / JDI-120022553

5.Ertan AK, Wagner S, Hendrik HJ, Tanriverdi HA, Schmidt W. Clinical and biophysical aspects of HELLP syndrome. J Perinat Honey. 2002; 30: 483–489. doi: 10.1515 / JPM.2002.076

6.Magann EF, Martin JN, Jr. Twelve Steps to Optimal Management of HELLP Syndrome. Gyneol Clin Obstet. 1999; 42: 532-550. doi: 10.1097 / 00003081-199909000-00009

7.Matsuda M, Mitsuhashi S, Watarai M, Yamamoto K, Hashimoto T, Ikeda S. Hemolysis, elevated liver enzymes and low platelet syndrome (HELLP) associated with systemic lupus erythematosus. Int. 2003; 42: 1052–1053. doi: 10.2169/internalmedicine.42.1052

8.Murphy MA, Ayazifar M. Permanent visual impairment, secondary to AD syndrome. J Neuroophthalmol. 2005; 25: 122–127. doi:10.1097/ICB.0000000000000249

9.Sibai BM, Ramadan MK, Mouth I, Salama M, Mercer BM, Friedman SA. Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome) Am J Obstet Gynecol. 1993; 169: 1000–1006.doi:10.1016/0002-9378(95)90099-3

10.Karumanchi SA, Maynard SE, Stillman IE, Epstein FH, Suhatme VP. Preeclampsia: a renal perspective. Kidney Int. 2005; 67: 2101-2113. doi: 10.1111 / j.1523-1755.2005.00316.x

11.Shiba BM. Diagnosis, controversy and management of hemolysis syndrome, elevation of liver enzymes and low platelet count. Obstet Gynecol. 2004; 103: 981–1991.doi:10.1097/01.AOG.0000126245.35811.2a

12.Barton JR, Sibai BM. Diagnosis and treatment of hemolysis, elevation of liver enzymes and low platelet syndrome. Clin Perinatol. 2004; 31: 807–33. doi: 10.1016 / j.clp.2004.06.008

13.Reubinoff BE, Schenker JG. HELLP syndrome--a syndrome of hemolysis, elevated liver enzymes and low platelet count--complicating preeclampsia-eclampsia. Int J Gynaecol Obstet 1991; 36:95.

14.Koenen SV, Huisjes AJ, Dings J, van der GY, Visser GH, Bruinse HW. Is There A Daily Picture Of Clinical Symptoms Of HELLР Syndrome? J Matern Fetal neonatal honey. 2006; 19: 93–99. doi: 10.1080 / 14767050500380976


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Published
2019-09-04
How to Cite
Lebid, L., Snisar, L., & Liksunova, L. (2019). HELLP syndrome against the background of glomerulonephritis: Clinical casereport. Ukrainian Journal of Nephrology and Dialysis, (3(63), 27-30. https://doi.org/10.31450/ukrjnd.3(63).2019.04