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COVID-19 and chronic kidney disease: peculiarities of treatment

O. Chernatska Sumy State University https://orcid.org/0000-0001-9093-6862
A. Grek Sumy State University https://orcid.org/0000-0002-6912-5990

DOI: https://doi.org/10.31450/ukrjnd.2(74).2022.11

Keywords: chronic kidney disease, COVID-19, statins, angiotensin-converting enzyme inhibitors.

Abstract

Abstract. The present study aimed to characterize the management of patients with chronic kidney disease with concomitant COVID-19. Articles published in 2019-2021 in the PubMed, Scopus, and Google Scholar electronic databases were analyzed.

As a result of this review, the following particularities of COVID-19 treatment in chronic kidney disease could be summarized. It is obligatory to continue treatment with renin-angiotensin-aldosterone system inhibitors in patients with chronic kidney disease and COVID-19. Lisinopril is considered used for avoiding the elevated renal expression of angiotensin-converting enzyme 2. Spironolactone can prevent acute lung injuries and is reasonable if the triple combination of drugs for reducing blood pressure is not effective. Low-dose rosuvastatin therapy is recommended for patients with COVID-19 and chronic kidney disease stages 3-5 treated with antiretroviral drugs such as lopinavir and ritonavir, remdesivir. Ezetimibe is reasonable to use in case of ineffective higher doses of statins and to decrease hospitalization risk.

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2022-06-06

How to Cite

Chernatska, O., & Grek, A. (2022). COVID-19 and chronic kidney disease: peculiarities of treatment. Ukrainian Journal of Nephrology and Dialysis, (2(74), 83-89. https://doi.org/10.31450/ukrjnd.2(74).2022.11

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No 2(74) (2022): Ukrainian Journal of Nephrology and Dialysis

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Nephrology School

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