Infections in the solid-organ transplant recipients

Manal El  Said

doi:10.31450/ukrjnd.2(70).2021.08

Manal El Said Медичний коледж Баттерджі; Теодор Білхарц Науково-дослідний інститут https://orcid.org/0000-0002-1090-1713

DOI: https://doi.org/10.31450/ukrjnd.2(70).2021.08

Ключові слова: реципієнт, солідний орган, трансплантація, інфекції, фактори ризику, хронологія, профілактика.

Анотація

Прогрес у галузі трансплантації привів до збільшення кількості реципієнтів трансплантату солідного органу (РТСО) та нових протистоянь з інфекційним ускладненнями, появою нещодавно контагіозних та стійких до антибактеріальних лікарських засобів мікроорганізмів. Профілактика інфекцій є наріжним каменем будь-якої сучасної програми трансплантації. Розуміння основ цих інфекцій з ранньою діагностикою має вирішальне значення для поліпшення результатів лікування РТСО. Імовірність критичних інфекцій у РТСО визначається залежно від епідеміологічного стану та імунної реакції реціпієнта. Покращення скринінгу, обстеження, включаючи візуалізацію і молекулярні методи дослідження та протоколи профілактичного втручання, продемонструвало перспективу зменшення інфекційних ускладнень та підвищення виживаності трансплантату. Передтрансплантаційний скринінг потенційного донора та реципієнта надає можливість прогностичної оцінки трансплантації, визначити посттрансплантаційні профілактичні та лікувальні підходи, вчасно діагностувати та вилікувати активну інфекцію та оновити стан вакцинації у потенційного реципієнта.

Завантаження

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Посилання

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