Thrombolysis for acute myocardial infarction in early post-renal transplant period: A case report

Abstract

Cardiovascular disease is a major contributor to morbidity and has become the leading cause of death among renal transplant patients. This paper presents a case of acute myocardial infarction occurring three weeks after a renal transplant. A 45-year-old male recipient experienced acute chest pain, hypotension, and atrial fibrillation, leading to a diagnosis of inferior-posterior wall myocardial infarction. Thrombolysis with Tenectaplase was administered, resulting in the development of a perinephric hematoma six hours later. The patient underwent transfusions and pigtail drainage of the hematoma. Following hematoma resolution, the pigtail catheter was removed, and the patient was started on dual anti-platelets. Upon discharge, the patient exhibited stable renal function. In conclusion, thrombolysis in the early post-transplant period poses significant risks. This case highlights the use of thrombolytic therapy during this period and the successful management of associated complications.